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DMT-2'-O-MOE-T-CE Phosphoramidite / 5-Me-DMT-2'-O-MOE-U-CE Phosphoramidite Amount/Package:25g / 250mL HDPE bottleDMT 2' O MOE T CE Phosphoramidite is a 2' MOE phosphoramidite monomer used for solid phase oligonucleotide synthesis. It contains a 5' dimethoxytrityl (DMT) protecting group for 5' hydroxyl protection, a thymine, a cyanoethyl (CE) protecting group on phosphite, and a 2' O methoxyethyl (MOE) modification. 2' O MOE provide enhanced nuclease resistance, duplex stability, and low cytotoxicity compared with unmodified RNA. Structurally, the 2' hydroxyl
ARCA prevents the reverse insertion of the cap structure through chemical modification
Stable disodium salt form: ensures consistent pH and long-term storage
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LNA-modified oligonucleotides show enhanced binding strength
acetyl (Ac) base-protecting group on 5-methylcytosine
a dimethylformamidyl (dmf) base-protecting group on guanine
Eliza Wyszko
JingHua Chen
High coupling efficiency and reproducibility in solid-phase DNA synthesis
TBDMS offers excellent stability for protecting 2'-hydroxyl of ribonucleosides during acid detritylation and oxidation steps
GuoNan Chen
US$ 247.50
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