Drug Delivery to the Brain: Physiological Concepts, Methodologies and Approaches (AAPS Advances in the Pharmaceutical Sciences Series, 33) [Hardcover] de Lange, Elizabeth C.M.; Hammarlund-Udenaes, Margareta and Thorne, Robert G. fbm where Rush Revere

where Rush Revere

18–25 by Yuki Tabata

and The Missing Sister — four unforgettable journeys inspired by the mythology of the Pleiades star cluster

as they take on wild villains — from mutant mathletes to cyborg substitutes and bake sale bandits

Drug Delivery to the Brain: Physiological Concepts, Methodologies and Approaches (AAPS Advances in the Pharmaceutical Sciences Series, 33) [Hardcover] de Lange, Elizabeth C.M.; Hammarlund-Udenaes, Margareta and Thorne, Robert G. fbm where Rush RevereThe development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the bloodbrain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e. g. active passive transport across the BBB, intra brain distribution, and central systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions